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SHUa Embarazo

SHUa Embarazo

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SHUa

SHUa

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INFORMACIÓN REGULATORIA  DE ACCESO AL TRATAMIENTO

  • Ficha Técnica, Informe Público Europeo de Evaluación (EPAR) y Prospecto de Soliris en la web de la Agencia Europea de Medicamentos (EMA):

DOCUMENTO PDF

  • Información para los profesionales sanitarios sobre Soliris en el tratamiento del SHUa:

https://www.ema.europa.eu/en/medicines/human/EPAR/soliris

  • Información para los pacientes y  sus cuidadores sobre Soliris en el tratamiento del SHUa:

https://cima.aemps.es/cima/publico/detalle.html?nregistro=07393001

  • Informe de evaluación y recomendaciones del NICE de eculizumab en el tratamiento del SHUa:

https://www.nice.org.uk/guidance/hst1/resources/eculizumab-for-treating-atypical-haemolytic-uraemic-syndrome-pdf-1394895848389

Publicaciones:

Diseases of complement dysregulation-an overview.

Wong EKS, Kavanagh D.

Semin Immunopathol. 2018 Jan;40(1):49-64. doi: 10.1007/s00281-017-0663-8. Epub 2018 Jan 11. Review.

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Purtscher-Like Retinopathy Associated with Atypical Hemolytic Uremic Syndrome.

Ustaoğlu M, Önder F, Solmaz N, Öztürk S, Ayer M.

Turk J Ophthalmol. 2017 Dec;47(6):348-350. doi: 10.4274/tjo.66502. Epub 2017 Dec 25.

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Atypical hemolytic-uremic syndrome due to complement factor I mutation.

Almalki AH, Sadagah LF, Qureshi M, Maghrabi H, Algain A, Alsaeed A.

World J Nephrol. 2017 Nov 6;6(6):243-250. doi: 10.5527/wjn.v6.i6.243.

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Atypical Hemolytic Uremic Syndrome: A Brief Review.

Zhang K, Lu Y, Harley KT, Tran MH.

Hematol Rep. 2017 Jun 1;9(2):7053. doi: 10.4081/hr.2017.7053. eCollection 2017 Jun 1. Review.

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Eculizumab in secondary atypical haemolytic uraemic syndrome.

Cavero T, Rabasco C, López A, Román E, Ávila A, Sevillano Á, Huerta A, Rojas-Rivera J, Fuentes C, Blasco M, Jarque A, García A, Mendizabal S, Gavela E, Macía M, Quintana LF, María Romera A, Borrego J, Arjona E, Espinosa M, Portolés J, Gracia-Iguacel C, González-Parra E, Aljama P, Morales E, Cao M, Rodríguez de Córdoba S, Praga M.

Nephrol Dial Transplant. 2017 Mar 1;32(3):466-474. doi: 10.1093/ndt/gfw453.

PMID: 28339660 [PubMed - indexed for MEDLINE] Free PMC Article

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Case report - atypical hemolytic uremic syndrome triggered by influenza B.

Kobbe R, Schild R, Christner M, Oh J, Loos S, Kemper MJ.

BMC Nephrol. 2017 Mar 20;18(1):96. doi: 10.1186/s12882-017-0512-y.

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An innovative and collaborative partnership between patients with rare disease and industry-supported registries: the Global aHUS Registry.

Woodward L, Johnson S, Walle JV, Beck J, Gasteyger C, Licht C, Ariceta G; aHUS Registry SAB.

Orphanet J Rare Dis. 2016 Nov 21;11(1):154. Review.

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Shen YM.

Thromb J. 2016 Oct 4;14(Suppl 1):19. eCollection 2016. Review.

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Clinical Practice Guidelines for the Management of Atypical Hemolytic Uremic Syndrome in Korea.

Cheong HI, Jo SK, Yoon SS, Cho H, Kim JS, Kim YO, Koo JR, Park Y, Park YS, Shin JI, Yoo KH, Oh D.

J Korean Med Sci. 2016 Oct;31(10):1516-28. doi: 10.3346/jkms.2016.31.10.1516.

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Genetic Atypical Hemolytic-Uremic Syndrome.

Noris M, Bresin E, Mele C, Remuzzi G.

In: Adam MP, Ardinger HH, Pagon RA, Wallace SE, Bean LJH, Stephens K, Amemiya A, editors.

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Terminal Complement Inhibitor Eculizumab in Adult Patients With Atypical Hemolytic Uremic Syndrome: A Single-Arm, Open-Label Trial.

Fakhouri F, Hourmant M, Campistol JM, Cataland SR, Espinosa M, Gaber AO, Menne J, Minetti EE, Provôt F, Rondeau E, Ruggenenti P, Weekers LE, Ogawa M, Bedrosian CL, Legendre CM.

Am J Kidney Dis. 2016 Jul;68(1):84-93. doi: 10.1053/j.ajkd.2015.12.034. Epub 2016 Mar 21.

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Improved renal recovery in patients with atypical hemolytic uremic syndrome following rapid initiation of eculizumab treatment.

Walle JV, Delmas Y, Ardissino G, Wang J, Kincaid JF, Haller H.

J Nephrol. 2017 Feb;30(1):127-134. doi: 10.1007/s40620-016-0288-3. Epub 2016 Mar 19.

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Recovery of renal function after long-term dialysis and resolution of cardiomyopathy in a patient with aHUS receiving eculizumab.

Emirova K, Volokhina E, Tolstova E, van den Heuvel B.

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Kidney Int. 2016 Mar;89(3):701-11. doi: 10.1016/j.kint.2015.11.026. Epub 2016 Jan 28.

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The global aHUS registry: methodology and initial patient characteristics.

Licht C, Ardissino G, Ariceta G, Cohen D, Cole JA, Gasteyger C, Greenbaum LA, Johnson S, Ogawa M, Schaefer F, Vande Walle J, Frémeaux-Bacchi V.

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Advances and challenges in the management of complement-mediated thrombotic microangiopathies.

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Posttransplant outcome of atypical haemolytic uraemic syndrome in a patient with thrombomodulin mutation: a case without recurrence.

Caroti L, Di Maria L, Carta P, Moscarelli L, Cirami C, Minetti EE.

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Role of the skin biopsy in the diagnosis of atypical hemolytic uremic syndrome.

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